Exosomes Derived from Mesenchymal Stem Cells Inhibit Catabolism in Human Chondrocytes by Activating Autophagy Via Inhibition of the NF-Κb Pathway
نویسندگان
چکیده
Objective: We aimed to determine the significance of MSC-derived exosomes (MSC-Exos) in chondrocyte autophagy under normal and inflammatory conditions.
منابع مشابه
Dihydroartemisinin inhibits catabolism in rat chondrocytes by activating autophagy via inhibition of the NF-κB pathway
Osteoarthritis is a disease with inflammatory and catabolic imbalance in cartilage. Dihydroartemisinin (DHA), a natural and safe anti-malarial agent, has been reported to inhibit inflammation, but its effects on chondrocytes have yet to be elucidated. We investigated the effects of DHA on catabolism in chondrocytes. Viability of SD rats chondrocytes was analyzed. Autophagy levels were determine...
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ژورنال
عنوان ژورنال: Journal of women's health and development
سال: 2022
ISSN: ['2644-2884']
DOI: https://doi.org/10.26502/fjwhd.2644-28840097